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Face of Tobias Ambjörnsson. Photo.

Tobias Ambjörnsson

Senior lecturer

Face of Tobias Ambjörnsson. Photo.

Stochastic approach to DNA breathing dynamics

Author

  • S. K Banik
  • T Ambjörnsson
  • R Metzler

Summary, in English

We propose a stochastic Gillespie scheme to describe the temporal fluctuations of local denaturation zones in double-stranded DNA as a single-molecule time series. It is demonstrated that the model recovers the equilibrium properties. We also study measurable dynamical quantities such as the bubble size autocorrelation function. This efficient computational approach will be useful to analyse in detail recent single-molecule experiments on clamped homopolymer breathing domains, to probe the parameter values of the underlying Poland-Scheraga model, as well as to design experimental conditions for similar setups.

Publishing year

2005-09-01

Language

English

Pages

852-858

Publication/Series

Europhysics Letters

Volume

71

Issue

5

Document type

Journal article

Publisher

EDP Sciences

Topic

  • Other Physics Topics

Status

Published

ISBN/ISSN/Other

  • ISSN: 0295-5075