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Face of Tobias Ambjörnsson. Photo.

Tobias Ambjörnsson

Senior lecturer

Face of Tobias Ambjörnsson. Photo.

Sensing DNA–DNA as Nanosensor: A Perspective Towards Nanobiotechnology

Author

  • Ralf Metzler
  • Tobias Ambjörnsson

Summary, in English

Based on modern single molecule techniques, we devise a number of possible experimental setups to probe local properties of DNA such as the presence of DNA-knots, loops or folds, or to obtain information on the DNA-sequence. Similarly, DNA may be used as a local sensor. Employing single molecule fluorescence methods, we propose to make use of the physics of DNA denaturation nanoregions to find out about the solvent conditions such as ionic strength, presence of binding proteins, etc. Bymeasuring dynamical quantities in particular, rather sensitive nanoprobes may be constructed with contemporary instruments.

Publishing year

2005-09-01

Language

English

Pages

389-395

Publication/Series

Journal of Computational and Theoretical Nanoscience

Volume

2

Issue

3

Document type

Journal article

Publisher

American Scientific Publishers

Topic

  • Physical Chemistry

Status

Published

ISBN/ISSN/Other

  • ISSN: 1546-1955